Complete Indicator Profile of Birth Defects: Prevalence of Hypoplastic Left Heart Syndrome per 10,000 Live Births
DefinitionHypoplastic left heart syndrome (HLHS) is a problem with the heart's structure that is present at birth (congenital). It is a group of related defects that, together, mean that the left side of the heart is underdeveloped. The prevalence of HLHS is the number of live-born infants with HLHS per 10,000 live born infants. (Live-born infants are the infants born with any evidence of life).
NumeratorNumber of live-born infants with hypoplastic left heart syndrome (HLHS).
DenominatorNumber of live-born infants.
Data Interpretation IssuesIn January 2000, birth defects became a reportable condition in New Mexico; however, birth defects were collected prior to this date. The first year of consistent data is 1998. However, data for hypoplastic left heart syndrome were not collected consistently until 2004. The most recent year of analyzed data is 2007.
Data are collected on live births occurring in-state to NM residents. Therefore, live births that occur in NM among out-of-state residents are excluded.
Case finding/identification occurs through review of birth and death certificates, hospital discharge diagnoses, records from pediatric specialists and prenatal diagnostic providers.
Birth defect cases are ascertained up to age 4; however, the majority of diagnoses are made by age 1.
Why Is This Important?Birth defects pose a significant public health problem. One in 33 babies is born with a structural birth defect in the United States. Birth defects are a leading cause of infant mortality and responsible for considerable morbidity and disability.
Among people with HLHS, the underdeveloped left side of the heart is unable to provide enough blood flow to the body. The normal shunts present at birth help to direct blood to the body; when these connections close the oxygen-rich blood supply decreases. Thus, babies with HLHS might look normal at birth, but will develop symptoms of HLHS within a few days. These symptoms might include:
-Ashen or bluish skin color
Without treatment, babies with HLHS die. Although this defect cannot be corrected, surgeries after birth can create the needed connections, or shunts, to allow the blood to get to the body.
Other ObjectivesCDC Environmental Public Health Tracking, Nationally Consistent Data and Measures (EPHT NCDM)
How Do We Compare With U.S.?The national prevalence of hypoplastic left heart among births from 2004-2006 is 2.3 per 10,000 births. These data data come from 14 birth defects surveillance programs: Arkansas, Arizona, California [8-county Central Valley], Colorado, Georgia [5-county metropolitan Atlanta], Illinois, Iowa, Kentucky, Massachusetts, North Carolina, Oklahoma, Puerto Rico, Texas, and Utah. Fore more information, please see: http://www.cdc.gov/ncbddd/features/birthdefects-keyfindings.html
Due to variability in the methods used by state birth defects surveillance systems and differences in populations and risk factors, state prevalence estimates may not be directly comparable with national estimates or those of other states.
Graphical Data Views
Data NotesNew Mexico live-born infants with hypoplastic left heart syndrome (HLHS), 2004-2007.
The following International Classification of Diseases, 9th Revision, Clinical Modification (ICD-9-CM) codes were used to identify HLHS: 746.7.
In 1987, CDC put forth a set of 6 digit codes (the sixth digit provides greater specificity for diagnosis) based on the British Pediatric Association Classification of Diseases and the ICD-9-CM. If CDC/BPA codes are present, the following were used to identify HLHS: 746.700.
More Resources and LinksEvidence-based community health improvement ideas and interventions may be found at the following sites:
Additional indicator data by state and county may be found on these Websites:
Medical literature can be queried at the PubMed website.
For an on-line medical dictionary, click on this Dictionary link.
Page Content Updated On 05/24/2011, Published on 06/23/2011